THYMOSIN BETA 4 (TB4)
TB4 is not a growth factor; rather, it is a major actin regulating peptide. TB4 has been found to play an important role in the protection, regeneration, and remodeling of injured or damaged tissues. The gene for TB4 has also been found to be one of the first to be up-regulated after a wound occurs.
Thymosin Beta 4 is a synthetic version of the naturally occurring peptide present in virtually all human cells.
Thymosin Beta-4 is a protein that consists of 43 amino acids and is encoded by the gene TMSB4X in the human body. It has been studied in numerous clinical trials. Research has shown that if the thymosin beta-4 peptide is used after a heart attack it can reactivate cardiac progenitor cells to repair damaged heart tissue.
Thymosin beta-4 is a very large molecule. In fact, it is so large that it cannot fit entirely into the receptor. Different sections of the molecule have different activities. TB-500 is the part of the thymosin beta-4 hormone which promotes the most useful effects (overall healing, repair, new blood, and muscle cells). For medical applications, it is more practical to use the TB-500 instead of the entire Thymosin Beta-4 protein.